CDC25C — Cell division cycle 25C
CDC25C belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
CDC25C's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD8⁺ T cells | G2/M Cell Cycle Cell cycle | CCNF, CDCA3, CDCA8, DEPDC1B, FAM83D, FBXO43, HJURP, PRC1 +1 more | View in SCUBA |
About the gene
| Synonyms | CDC25, PPP1R60 |
|---|---|
| Chromosome | 5: 138285269-138338355 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Cancer-related genes, Enzymes, Predicted intracellular proteins |
| Molecular function | Hydrolase, Protein phosphatase |
| Biological process | Cell cycle, Cell division, Host-virus interaction, Mitosis |
Function
Functions as a dosage-dependent inducer in mitotic control. Tyrosine protein phosphatase required for progression of the cell cycle. When phosphorylated, highly effective in activating G2 cells into prophase. Directly dephosphorylates CDK1 and activates its kinase activity
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.