CDIP1 — Cell death inducing p53 target 1
CDIP1 belongs to a gene co-expression module in 2 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
CDIP1's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD4⁺ T cells | NF-kB feedback TCR/AP1/NFKb pathway | ADTRP, AKAP5, CDKN2A, CLEC7A, INPP1, MAP3K5, N4BP1, PBXIP1 +8 more | View in SCUBA |
| Gamma-delta T cells | DNA Repair Housekeeping Housekeeping | ANAPC16, CCDC85B, CKLF, COTL1, DNAJC4, ECH1, ERCC1, IFT27 +10 more |
About the gene
| Synonyms | C16orf5, CDIP, LITAFL |
|---|---|
| Chromosome | 16: 4510669-4538828 |
| Predicted location | Intracellular, Membrane |
| Essential gene | No |
| Protein class | Predicted intracellular proteins, Predicted membrane proteins |
| Biological process | Apoptosis |
Function
Acts as an important p53/TP53-apoptotic effector. Regulates TNF-alpha-mediated apoptosis in a p53/TP53-dependent manner
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.