CCDC85B — Coiled-coil domain containing 85B
CCDC85B belongs to a gene co-expression module in 10 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
CCDC85B's module in each cell type
About the gene
| Synonyms | DIPA |
|---|---|
| Chromosome | 11: 65890673-65891635 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Predicted intracellular proteins |
| Molecular function | Repressor |
| Biological process | Differentiation, Growth regulation, Host-virus interaction, Transcription, Transcription regulation |
Function
Functions as a transcriptional repressor. May inhibit the activity of CTNNB1 in a TP53-dependent manner and thus regulate cell growth. May function in adipocyte differentiation, negatively regulating mitotic clonal expansion (By similarity). Plays a role in cell-cell adhesion and epithelium development through its interaction with proteins of the beta-catenin family (By similarity). (Microbial infection) Plays a role in hepatitis delta virus (HDV) genomic replication
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.