DCAF6 — DDB1 and CUL4 associated factor 6
DCAF6 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
DCAF6's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Macrophages | Innate Immune Dampening Innate immunity | ELL2, FGD4, FKBP5, IRAK3, MAP2K4, MOB3B, PACSIN2, PAPSS2 +10 more | View in SCUBA |
About the gene
| Synonyms | IQWD1, PC326 |
|---|---|
| Chromosome | 1: 167935783-168075843 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Predicted intracellular proteins |
| Biological process | Ubl conjugation pathway |
Function
Ligand-dependent coactivator of nuclear receptors. Enhance transcriptional activity of the nuclear receptors NR3C1 and AR. May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex.
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.