DCTN6 — Dynactin subunit 6
DCTN6 belongs to a gene co-expression module in 2 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
DCTN6's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD4⁺ T cells | TCR signaling TCR/AP1/NFKb pathway | AP3M2, ATP1B3, CREM, CRYBG1, EZR, FAM177A1, FTH1, GCSAM +19 more | View in SCUBA |
| Innate lymphoid cells | NK ILC Tissue Homing Homing & TEM | ADGRE5, AKAP13, AREG, ARL4C, ATP1B3, B3GNT7, BTG1, CCDC107 +25 more | View in SCUBA |
About the gene
| Synonyms | WS-3 |
|---|---|
| Chromosome | 8: 30156319-30183639 |
| Predicted location | Intracellular |
| Essential gene | Yes |
| Protein class | Essential proteins, Predicted intracellular proteins |
Function
Part of the dynactin complex that activates the molecular motor dynein for ultra-processive transport along microtubules
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.