BTG1 — BTG anti-proliferation factor 1

BTG1 belongs to a gene co-expression module in 14 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.

BTG1's module in each cell type

Cell type	Module	Shares the module with
CD19⁺ B cells	B cell quiescence BCR/AP1/NFKb pathway	AREG, CD55, CXCR4, LY9, PNRC1, TUBA1A, YPEL5, ZFP36L2	View in SCUBA
CD4⁺ T cells	Glucocorticoid Immunoregulation Immune regulation	AHNAK, CRIP1, GGNBP2, IDS, INSIG1, IRS2, JUND, KLF6 +11 more	View in SCUBA
Endothelial	Notch Arterial Identity Endothelial cell development	ADAMTS1, ARID5A, BTG2, CRIP1, DLL4, EFNA1, EFNB2, GADD45A +14 more	View in SCUBA
Enterocytes	Mature colonocyte absorptive Absorption	ADI1, BRI3, CAMK2N1, CTSZ, FXYD3, GUCA2A, GUCA2B, HSD17B2 +9 more	View in SCUBA
Fibroblasts	Fibroblast Quiescence Housekeeping	EIF1, EIF4A2, FNIP1, ID2, KLF2, KLF4, RHOB, SRSF5 +5 more	View in SCUBA
Gamma-delta T cells	TCR Early Activation TCR Signaling	BTG2, CD69, CIRBP, CXCR4, DUSP1, EIF1, ETV3, FOS +15 more
Goblet cells	mRNA Stability Control RNA processing & translation	DNAJB6, PNRC1, SRSF5, TENT5C, TSC22D1, TUBA1A, TXNIP, UBXN1 +5 more	View in SCUBA
Innate lymphoid cells	NK ILC Tissue Homing Homing & TEM	ADGRE5, AKAP13, AREG, ARL4C, ATP1B3, B3GNT7, CCDC107, CCR6 +25 more	View in SCUBA
Macrophages	Hypoxia-driven Activation Inflammatory	ACVR1B, ADAM10, ADAM9, ALCAM, ANO6, B3GNT2, C5AR1, CAB39 +33 more	View in SCUBA
Monocytes	TREM1 Inflammatory Signaling Innate immunity	AGO2, AKAP12, ATP2B1, B3GNT5, C17orf107, CHRNE, ERRFI1, IL1R1 +6 more	View in SCUBA
Mucosal-associated invariant T cell	mRNA Decay Program RNA processing & translation	ATP6V0C, BCL7B, BTG3, CCDC59, DDIT4, DUSP2, DYNLL2, EXOSC6 +13 more
Natural Killer cells	AP-1 Immediate Early activation	CITED2, CXCR4, DUSP1, DUSP2, FOS, JUN, JUNB, KLF6 +1 more	View in SCUBA
Neutrophils	Inflammatory Resolution Stress	ARL5B, ATG2A, ATP2B1, CREM, DDIT4, FOSL2, GPR65, JOSD1 +4 more
Smooth muscle cells	Immediate Early Response Stress	ATF3, BTG2, CDKN1A, EGR1, FOS, GADD45B, HES1, IER2 +7 more	View in SCUBA

About the gene

Synonyms	APRO2
Chromosome	12: 92140278-92145846
Predicted location	Intracellular
Essential gene	No
Protein class	Cancer-related genes, Disease related genes, Predicted intracellular proteins

Function

Anti-proliferative protein

Human Protein Atlas · Open Targets · UniProt

Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.