AREG — Amphiregulin
AREG belongs to a gene co-expression module in 10 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
AREG's module in each cell type
About the gene
| Synonyms | AR, AREGB, SDGF |
|---|---|
| Chromosome | 4: 74445136-74455005 |
| Predicted location | Membrane |
| Essential gene | No |
| Protein class | Cancer-related genes, Human disease related genes, Predicted membrane proteins |
| Molecular function | Cytokine, Growth factor |
Function
Ligand of the EGF receptor/EGFR. Autocrine growth factor as well as a mitogen for a broad range of target cells including astrocytes, Schwann cells and fibroblasts
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.