DNAH8 — Dynein axonemal heavy chain 8
DNAH8 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
DNAH8's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD4⁺ T cells | Regulatory T cell Immune regulation | ACTA2, APOLD1, ATP13A3, CARD16, CD27, CD79B, FAM184A, HS3ST3B1 +7 more | View in SCUBA |
About the gene
| Synonyms | hdhc9 |
|---|---|
| Chromosome | 6: 38715311-39030792 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins |
| Molecular function | Motor protein |
Function
Force generating protein component of the outer dynein arms (ODAs) in the sperm flagellum. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Involved in sperm motility; implicated in sperm flagellar assembly
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.