ACTA2 — Actin alpha 2, smooth muscle
ACTA2 belongs to a gene co-expression module in 4 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
ACTA2's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD4⁺ T cells | Regulatory T cell Immune regulation | APOLD1, ATP13A3, CARD16, CD27, CD79B, DNAH8, FAM184A, HS3ST3B1 +7 more | View in SCUBA |
| Fibroblasts | Myofibroblast Contractile Cytoskeletal | CCDC107, CFL2, CSRP1, FLNA, ILK, LPP, MSRB3, MYL9 +7 more | View in SCUBA |
| Pericytes | Smooth Muscle Contractile Cytoskeletal | CSRP1, FLNA, MYL9, MYLK, NEXN, PPP1R14A, S100A4, TAGLN +2 more | View in SCUBA |
| Smooth muscle cells | SMC contractile apparatus Contractility | ACTB, CALD1, CAV1, DSTN, MYL6, MYL9, PPP1R14A, SH3BGRL +2 more | View in SCUBA |
About the gene
| Synonyms | ACTSA |
|---|---|
| Chromosome | 10: 88935074-88991339 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins |
| Molecular function | Hydrolase, Muscle protein |
Function
Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.