SCUBA

DNAJC21 — DnaJ heat shock protein family (Hsp40) member C21

DNAJC21 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.

DNAJC21's module in each cell type

Cell typeModuleShares the module with
MacrophagesProtein Biogenesis
Housekeeping
ATP6V0D1, B3GAT3, BUD23, C11orf58, CHD4, CNPY2, DAZAP1, DDX46 +23 moreView in SCUBA

About the gene

SynonymsDNAJA5, GS3, JJJ1
Chromosome5: 34929559-34958964
Predicted locationIntracellular
Essential geneNo
Protein classDisease related genes, Human disease related genes, Predicted intracellular proteins
Molecular functionChaperone

Function

May act as a co-chaperone for HSP70. May play a role in ribosomal RNA (rRNA) biogenesis, possibly in the maturation of the 60S subunit. Binds the precursor 45S rRNA

Human Protein Atlas · Open Targets · UniProt

Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.