CNPY2 — Canopy FGF signaling regulator 2
CNPY2 belongs to a gene co-expression module in 5 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
CNPY2's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD4⁺ T cells | Protein/ER secretory machinery Protein processing & ER | ACTR2, ATP5IF1, ATP5ME, BAZ1B, CMC2, COMMD3, COPZ1, CRY1 +16 more | View in SCUBA |
| Gamma-delta T cells | T Cell Homeostasis Housekeeping | ATP6V0E1, CALHM2, CSK, CSTB, DAD1, FERMT3, GTF2H5, MYL12A +11 more | |
| Innate lymphoid cells | Mitochondrial OxPhos Mitochondrial & OxPhos | AKR7A2, ANXA6, AP2M1, ARL6IP4, ARPC1B, ATP5MC2, ATP5PB, BSG +21 more | View in SCUBA |
| Macrophages | Protein Biogenesis Housekeeping | ATP6V0D1, B3GAT3, BUD23, C11orf58, CHD4, DAZAP1, DDX46, DNAJA2 +23 more | View in SCUBA |
| Mucosal-associated invariant T cell | Mitochondrial Ribosome Mitochondrial & OxPhos | AGTRAP, BRK1, C11orf68, C14orf119, CZIB, DCTPP1, DYNC1I2, FOXN2 +22 more |
About the gene
| Synonyms | HP10390, TMEM4, ZSIG9 |
|---|---|
| Chromosome | 12: 56309842-56316119 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Plasma proteins, Predicted intracellular proteins |
Function
Positive regulator of neurite outgrowth by stabilizing myosin regulatory light chain (MRLC). It prevents MIR-mediated MRLC ubiquitination and its subsequent proteasomal degradation
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.