ENO2 — Enolase 2
ENO2 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
ENO2's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD4⁺ T cells | Mixed Metabolic Ambient Technical artifact | DPYD, FABP6, FCGRT, GRAP, SMURF2, SPINK2, SYNJ2BP, TNFRSF10B +1 more | View in SCUBA |
About the gene
| Synonyms | NSE |
|---|---|
| Chromosome | 12: 6913745-6923698 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Cancer-related genes, Candidate cardiovascular disease genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins |
| Molecular function | Lyase |
| Biological process | Glycolysis |
Function
Has neurotrophic and neuroprotective properties on a broad spectrum of central nervous system (CNS) neurons. Binds, in a calcium- dependent manner, to cultured neocortical neurons and promotes cell survival (By similarity)
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.