ENTPD2 — Ectonucleoside triphosphate diphosphohydrolase 2
ENTPD2 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
ENTPD2's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Glial cells | Enteric Glial Homeostasis Housekeeping | APOE, BCHE, CCND3, COL12A1, FXYD6, NPDC1, PAQR6, PCSK1N +5 more | View in SCUBA |
About the gene
| Synonyms | CD39L1, NTPDase-2 |
|---|---|
| Chromosome | 9: 137048107-137054061 |
| Predicted location | Membrane |
| Essential gene | No |
| Protein class | Metabolic proteins, Predicted membrane proteins |
| Molecular function | Hydrolase |
Function
In the nervous system, could hydrolyze ATP and other nucleotides to regulate purinergic neurotransmission. Hydrolyzes ADP only to a marginal extent. The order of activity with different substrates is ATP > GTP > CTP = ITP > UTP >> ADP = UDP
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.