FGF12 — Fibroblast growth factor 12
FGF12 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
FGF12's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Endothelial | Endothelial Junction Identity Endothelial cell development | ADGRF5, AKAP13, CDH5, CXCL12, DENND5A, FURIN, HSPA12B, NES +13 more | View in SCUBA |
About the gene
| Synonyms | FGF12B, FHF1 |
|---|---|
| Chromosome | 3: 192139390-192767764 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Disease related genes, Human disease related genes, Predicted intracellular proteins |
| Molecular function | Growth factor |
Function
Involved in nervous system development and function. Involved in the positive regulation of voltage-gated sodium channel activity. Promotes neuronal excitability by elevating the voltage dependence of neuronal sodium channel SCN8A fast inactivation
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.