FRAT2 — FRAT regulator of WNT signaling pathway 2
FRAT2 belongs to a gene co-expression module in 2 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
FRAT2's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Gamma-delta T cells | AP-1 Immediate Early Response Stress | BRD2, CITED2, CSKMT, EGR1, EIF4A2, FRAT1, GADD45B, HEXIM1 +25 more | |
| Neutrophils | Neutrophil Differentiation Developmental | ABTB1, GCA, ICAM3, MANSC1, MNDA, MSL3, NFE2, QPCT +2 more |
About the gene
| Chromosome | 10: 97332497-97334729 |
|---|---|
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Predicted intracellular proteins |
| Biological process | Wnt signaling pathway |
Function
Positively regulates the Wnt signaling pathway by stabilizing beta-catenin through the association with GSK-3
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.