GJC2 — Gap junction protein gamma 2
GJC2 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
GJC2's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Lymphatic endothelial | Lymphatic Valve Formation Valve formation | A2M, CD34, CISD1, FAM89A, FHL3, FSCN1, GRAP, HTRA1 +5 more | View in SCUBA |
About the gene
| Synonyms | CX46.6, CX47, GJA12, SPG44 |
|---|---|
| Chromosome | 1: 228149930-228159826 |
| Predicted location | Membrane |
| Essential gene | No |
| Protein class | Disease related genes, Human disease related genes, Predicted membrane proteins |
Function
One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. May play a role in myelination in central and peripheral nervous systems
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.