SCUBA

HOXB3 — Homeobox B3

HOXB3 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.

HOXB3's module in each cell type

Cell typeModuleShares the module with
EndothelialNF-kB Chromatin Regulation
DNA/chromatin regulation
ARHGEF3, DGKE, HLA-E, IKBKB, ITPKB, KITLG, LIMCH1, MALT1 +4 moreView in SCUBA

About the gene

SynonymsHOX2, HOX2G
Chromosome17: 48548870-48604912
Predicted locationIntracellular
Essential geneNo
Protein classPlasma proteins, Predicted intracellular proteins, Transcription factors
Molecular functionDevelopmental protein, DNA-binding
Biological processTranscription, Transcription regulation

Function

Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis

Human Protein Atlas · Open Targets · UniProt

Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.