KIF16B — Kinesin family member 16B
KIF16B belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
KIF16B's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Macrophages | Transcriptional Regulation Housekeeping | ABCC4, ARHGAP12, ATP8B4, CBFA2T2, DLG1, FAM168A, FBXO42, FCHO2 +20 more | View in SCUBA |
About the gene
| Synonyms | C20orf23, dJ971B4.1, FLJ20135, SNX23 |
|---|---|
| Chromosome | 20: 16272104-16573448 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Predicted intracellular proteins |
| Molecular function | Motor protein |
| Biological process | Transport |
Function
Plus end-directed microtubule-dependent motor protein involved in endosome transport and receptor recycling and degradation. Regulates the plus end motility of early endosomes and the balance between recycling and degradation of receptors such as EGF receptor (EGFR) and FGF receptor (FGFR). Regulates the Golgi to endosome transport of FGFR-containing vesicles during early development, a key process for developing basement membrane and epiblast and primitive endoderm lineages during early postimplantation development
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.