SCUBA

ARHGAP12 — Rho GTPase activating protein 12

ARHGAP12 belongs to a gene co-expression module in 2 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.

ARHGAP12's module in each cell type

Cell typeModuleShares the module with
Gamma-delta T cellsT Cell Identity Program
T cell maturation
ADA2, ADAM10, ATM, LPP, NLRC5, PIKFYVE, PJA2, PRKCQ +5 more
MacrophagesTranscriptional Regulation
Housekeeping
ABCC4, ATP8B4, CBFA2T2, DLG1, FAM168A, FBXO42, FCHO2, FRMD4A +20 moreView in SCUBA

About the gene

SynonymsFLJ10971, FLJ20737, FLJ21785
Chromosome10: 31805398-31928876
Predicted locationIntracellular
Essential geneNo
Protein classPredicted intracellular proteins
Molecular functionGTPase activation

Function

GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state

Human Protein Atlas · Open Targets · UniProt

Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.