KXD1 — KxDL motif containing 1
KXD1 belongs to a gene co-expression module in 2 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
KXD1's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD4⁺ T cells | CD4 Lineage Identity T cell development | ACAA1, AGPAT3, ASCC3, ATF2, KIFAP3, NEK7, PARP4, PPM1A +6 more | View in SCUBA |
| Gamma-delta T cells | Transcriptional Elongation Control DNA/chromatin regulation | ANP32B, AP2M1, ARF5, AURKAIP1, CCDC124, CUEDC2, CYC1, DCTN3 +19 more |
About the gene
| Synonyms | BORCS4, C19orf50, FLJ25480, KXDL, MGC2749 |
|---|---|
| Chromosome | 19: 18557762-18569387 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Predicted intracellular proteins |
Function
As part of the BORC complex may play a role in lysosomes movement and localization at the cell periphery. Associated with the cytosolic face of lysosomes, the BORC complex may recruit ARL8B and couple lysosomes to microtubule plus-end-directed kinesin motor. May be involved in the biogenesis of lysosome- related organelles such as melanosomes (By similarity)
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.