LEFTY1 — Left-right determination factor 1
LEFTY1 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
LEFTY1's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Goblet cells | Mature Colonocyte Function Epithelial development | ADD3, CERS6, CFTR, GAS6, MAOA, NOX1, PDCD4, PLBD1 +2 more | View in SCUBA |
About the gene
| Synonyms | LEFTB, LEFTYB |
|---|---|
| Chromosome | 1: 225886282-225911382 |
| Predicted location | Secreted |
| Essential gene | No |
| Protein class | Predicted secreted proteins |
| Molecular function | Cytokine, Developmental protein, Growth factor |
Function
Required for left-right axis determination as a regulator of LEFTY2 and NODAL
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.