LRP12 — LDL receptor related protein 12
LRP12 belongs to a gene co-expression module in 2 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
LRP12's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD4⁺ T cells | Leukocyte Motility migration & adhesion | ATP2A3, HSH2D, LZTFL1, MYO1G, MYO9B, NBEAL2, PPARG, TBC1D31 +1 more | View in SCUBA |
| Macrophages | Osmotic Stress Response Stress | ANKRD28, BZW1, CD109, CXCL8, CYB5R4, CYTIP, DUSP4, EMP3 +25 more | View in SCUBA |
About the gene
| Synonyms | FLJ12929, ST7 |
|---|---|
| Chromosome | 8: 104489231-104589258 |
| Predicted location | Membrane |
| Essential gene | No |
| Protein class | Disease related genes, Human disease related genes, Predicted membrane proteins |
| Molecular function | Receptor |
| Biological process | Endocytosis |
Function
Probable receptor, which may be involved in the internalization of lipophilic molecules and/or signal transduction. May act as a tumor suppressor
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.