EMP3 — Epithelial membrane protein 3

EMP3 belongs to a gene co-expression module in 13 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.

EMP3's module in each cell type

Cell type	Module	Shares the module with
CD19⁺ B cells	Membrane adhesion remodeling migration & adhesion	ARL6IP5, ATP6V0E1, CAMK1D, CAST, CELF2, DDAH2, FLNA, FXYD5 +6 more	View in SCUBA
CD4⁺ T cells	Cytotoxic effector Cytotoxicity	ADAM23, CTSW, FKBP2, IFITM2, IGFBP3, KLRG1, LYAR, PLP2 +11 more	View in SCUBA
Endothelial	Vascular Homeostasis Endothelial cell development	ATP2A3, ATP6V1C2, C19orf33, CP, ICAM2, MERTK, PLLP, PPP1R14A +5 more	View in SCUBA
Fibroblasts	Proteolytic Fibroblast State ECM remodeling	ANXA2, CTSK, LGALS3, MPZL1, PCOLCE, ROBO1, S100A10, S100A16 +3 more	View in SCUBA
Gamma-delta T cells	Effector IFN Response cytotoxicity	AGTRAP, ANXA1, B2M, CYBA, FXYD5, GZMM, IFITM1, IFITM2 +9 more
Glial cells	S100 Glial Activation Activation	CDC42EP5, CREB5, CRIP2, S100A10, S100A4, S100A6, TPPP3	View in SCUBA
Hematopoietic progenitor cells	ER Protein Folding Housekeeping	ASRGL1, CALR, CD63, CHPT1, GLUL, HSPA5, IDH2, MLEC +13 more
Innate lymphoid cells	NK Homing Circulating Homing & TEM	ADD3, ANXA1, APOBEC3G, C16orf54, C1orf162, CAPG, CASP4, CAST +37 more	View in SCUBA
Macrophages	Osmotic Stress Response Stress	ANKRD28, BZW1, CD109, CXCL8, CYB5R4, CYTIP, DUSP4, FURIN +25 more	View in SCUBA
Mucosal-associated invariant T cell	Cytotoxic Lymphocyte Program cytotoxicity	ANXA11, CDKN2D, CYB5A, ETHE1, FLT3LG, GLIPR2, LDHB, LTB +9 more
Natural Killer cells	Granulysin Cytotoxic Effector Cytotoxicity	ARL4C, DSTN, FLNA, GNLY, S100A4, S100A6, TIMP1, VCL	View in SCUBA
Pericytes	Actin Dynamics Cytoskeletal	ARPC1A, CCND1, DSTN, MGST3, NDUFA4, PTP4A3, S100A6	View in SCUBA
Smooth muscle cells	Generic maintenance transcripts Housekeeping	CHMP2A, HMGN1, MRPL57, NCKAP1, PAIP2, PSMB2, SLC25A5, TAX1BP3 +5 more	View in SCUBA

About the gene

Synonyms	YMP
Chromosome	19: 48321509-48330553
Predicted location	Intracellular, Membrane
Essential gene	No
Protein class	Predicted intracellular proteins, Predicted membrane proteins

Function

Probably involved in cell proliferation and cell-cell interactions

Human Protein Atlas · Open Targets · UniProt

Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.