LTB4R2 — Leukotriene B4 receptor 2
LTB4R2 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
LTB4R2's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Gamma-delta T cells | Immune Synapse Cytoskeleton Cytoskeletal | ARHGAP4, ARHGAP45, ATP2A3, CD48, DDOST, ICAM3, IL32, LAPTM5 +8 more |
About the gene
| Synonyms | BLT2, BLTR2, JULF2, NOP9 |
|---|---|
| Chromosome | 14: 24305734-24312053 |
| Predicted location | Membrane |
| Essential gene | No |
| Protein class | G-protein coupled receptors, Predicted membrane proteins |
| Molecular function | G-protein coupled receptor, Receptor, Transducer |
Function
Low-affinity receptor for leukotrienes including leukotriene B4. Mediates chemotaxis of granulocytes and macrophages. The response is mediated via G-proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinities for the leukotrienes is LTB4 > 12-epi-LTB4 > LTB5 > LTB3
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.