SCUBA

LAPTM5 — Lysosomal protein transmembrane 5

LAPTM5 belongs to a gene co-expression module in 9 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.

LAPTM5's module in each cell type

Cell typeModuleShares the module with
CD19⁺ B cellsMHC-II antigen presentation
B cell maturation
CD53, CD81, CYTH1, DAPP1, DNAJC10, FAM3C, FCRLA, GPR18 +11 moreView in SCUBA
CD4⁺ T cellsTCR Complex Activation
TCR/AP1/NFKb pathway
ABHD17A, ACTR3, C1GALT1, CD2, CD3D, CD3E, CD3G, CD81 +14 moreView in SCUBA
CD8⁺ T cellsTCR Complex Signaling
TCR Signaling
ACAP1, ANXA1, CD37, CD3E, CITED2, DUSP1, EVL, LCK +4 moreView in SCUBA
EndothelialArterial EC Identity
Endothelial cell development
CCDC71L, FABP4, MAP3K1, MDK, PCBD1, PMVK, RASSF4, SCNN1B +2 moreView in SCUBA
Gamma-delta T cellsImmune Synapse Cytoskeleton
Cytoskeletal
ARHGAP4, ARHGAP45, ATP2A3, CD48, DDOST, ICAM3, IL32, LTB4R2 +8 more
Innate lymphoid cellsmRNA Translation
RNA processing & translation
ABHD14B, ARHGDIA, CD2BP2, EEF2, EIF3L, GYPC, H2AJ, HNRNPA0 +6 moreView in SCUBA
Mucosal-associated invariant T cellCo-transcriptional Splicing
RNA processing & translation
C9orf78, CCDC85C, CCNK, CDKN1B, DNTTIP2, EIF4B, ILF3, MADD +16 more
Natural Killer cellsLymphocyte Trafficking
Homing & TEM
BCL6, CTSD, LITAF, ORAI1, P2RY8, PTPRJ, RNF166, S1PR1 +3 moreView in SCUBA
NeutrophilsC5aR Complement Activation
Innate immunity
ADGRG3, C5AR1, CD55, ITPRIP, MCL1, PFKFB3, PTPRE, RYBP +3 more

About the gene

Chromosome1: 30732469-30757774
Predicted locationMembrane
Essential geneNo
Protein classPredicted membrane proteins, Transporters
Biological processTransport

Function

May have a special functional role during embryogenesis and in adult hematopoietic cells

Human Protein Atlas · Open Targets · UniProt

Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.