MMRN2 — Multimerin 2
MMRN2 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
MMRN2's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Endothelial | Hypoxia-IFN Endothelial Endothelial cell development | BCAM, CRIP2, EPAS1, FES, HEG1, IFI27, IFITM1, LIMA1 +8 more | View in SCUBA |
About the gene
| Synonyms | EMILIN3, EndoGlyx-1, FLJ13465 |
|---|---|
| Chromosome | 10: 86935540-86969481 |
| Predicted location | Intracellular, Secreted |
| Essential gene | No |
| Protein class | Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins |
| Biological process | Angiogenesis |
Function
Extracellular matrix protein that plays significant roles in the vascular system and is required for the maintenance and stability of blood vessel. Affects several essential steps in angiogenesis including endothelial cell proliferation, migration, and tube formation. Positively regulates angiogenesis by acting as a ligand for CD93 receptor.
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.