NFE2L3 — NFE2 like bZIP transcription factor 3
NFE2L3 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
NFE2L3's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Monocytes | IFN-γ Monocyte Response Inflammatory | ANKRD22, APOL3, ATF5, CXCL9, HAPLN3, IL2RA, IL2RG, LYSMD2 +2 more | View in SCUBA |
About the gene
| Synonyms | Nrf3 |
|---|---|
| Chromosome | 7: 26152198-26187137 |
| Predicted location | Intracellular |
| Essential gene | Yes |
| Protein class | Essential proteins, Plasma proteins, Predicted intracellular proteins, Transcription factors |
| Molecular function | Activator, DNA-binding |
| Biological process | Transcription, Transcription regulation |
Function
Activates erythroid-specific, globin gene expression
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.