HAPLN3 — Hyaluronan and proteoglycan link protein 3
HAPLN3 belongs to a gene co-expression module in 5 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
HAPLN3's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Endothelial | Leukocyte Recruitment Signaling Inflammation | BIRC3, CELSR1, CSF2RB, HSD3B7, IL34, IL7R, LTF, OLFM1 +6 more | View in SCUBA |
| Fibroblasts | NF-κB Inflammatory Activation Inflammatory | BIRC3, CD40, CTSS, DRAM1, IL15RA, IL32, LAP3, STAT1 +5 more | View in SCUBA |
| Glial cells | NF-κB/IFN Inflammatory Inflammation | BIRC3, CTSS, CXCL10, CXCL2, CXCL9, FDCSP, ICAM1, PTX3 +4 more | View in SCUBA |
| Monocytes | IFN-γ Monocyte Response Inflammatory | ANKRD22, APOL3, ATF5, CXCL9, IL2RA, IL2RG, LYSMD2, NFE2L3 +2 more | View in SCUBA |
| Smooth muscle cells | BMP-ID3 Matricellular Development | ANXA1, DKK3, ID3, SH3BGRL3, SMOC2, STOM, TAGLN2 | View in SCUBA |
About the gene
| Synonyms | EXLD1, HsT19883 |
|---|---|
| Chromosome | 15: 88877294-88895597 |
| Predicted location | Membrane, Secreted |
| Essential gene | No |
| Protein class | Predicted membrane proteins, Predicted secreted proteins |
Function
May function in hyaluronic acid binding
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.