CXCL9 — C-X-C motif chemokine ligand 9
CXCL9 belongs to a gene co-expression module in 5 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
CXCL9's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Endothelial | IFN-gamma Response Inflammation | APOL2, APOL6, BATF2, CARD16, CASP1, CD40, CXCL10, CXCL11 +18 more | View in SCUBA |
| Fibroblasts | IFN-γ MHC-II Response Inflammatory | CALHM6, CD74, CXCL11, GBP4, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DRA +3 more | View in SCUBA |
| Glial cells | NF-κB/IFN Inflammatory Inflammation | BIRC3, CTSS, CXCL10, CXCL2, FDCSP, HAPLN3, ICAM1, PTX3 +4 more | View in SCUBA |
| Macrophages | IFN-gamma Response Inflammatory | ANKRD22, APOL2, ATF5, ATP13A1, CD274, CD300LF, CD40, CD48 +21 more | View in SCUBA |
| Monocytes | IFN-γ Monocyte Response Inflammatory | ANKRD22, APOL3, ATF5, HAPLN3, IL2RA, IL2RG, LYSMD2, NFE2L3 +2 more | View in SCUBA |
About the gene
| Synonyms | CMK, crg-10, Humig, MIG, SCYB9 |
|---|---|
| Chromosome | 4: 76001275-76007509 |
| Predicted location | Secreted |
| Essential gene | No |
| Protein class | Cancer-related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins |
| Molecular function | Cytokine |
| Biological process | Inflammatory response |
Function
Cytokine that affects the growth, movement, or activation state of cells that participate in immune and inflammatory response. Chemotactic for activated T-cells. Binds to CXCR3
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.