NUP205 — Nucleoporin 205
NUP205 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
NUP205's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Gamma-delta T cells | DNA Damage Response DNA/chromatin regulation | AP1B1, CCAR1, CHD8, DOCK2, EP400, ERBIN, GOLM2, IPO8 +17 more |
About the gene
| Synonyms | C7orf14, KIAA0225 |
|---|---|
| Chromosome | 7: 135557917-135648757 |
| Predicted location | Intracellular, Membrane |
| Essential gene | Yes |
| Protein class | Disease related genes, Essential proteins, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters |
| Biological process | mRNA transport, Protein transport, Translocation, Transport |
Function
Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance. May anchor NUP62 and other nucleoporins, but not NUP153 and TPR, to the NPC. In association with TMEM209, may be involved in nuclear transport of various nuclear proteins in addition to MYC.
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.