OIP5 — Opa interacting protein 5
OIP5 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
OIP5's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD8⁺ T cells | G2/M Checkpoint Cell cycle | CCDC34, CDCA4, CDCA5, MND1, MYBL2, RAD54L, RRM2, SAC3D1 +1 more | View in SCUBA |
About the gene
| Synonyms | CT86, hMIS18beta, MIS18B |
|---|---|
| Chromosome | 15: 41309273-41332591 |
| Predicted location | Intracellular |
| Essential gene | Yes |
| Protein class | Essential proteins, Predicted intracellular proteins |
| Biological process | Cell cycle, Cell division, Mitosis |
Function
Required for recruitment of CENPA to centromeres and normal chromosome segregation during mitosis
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.