MYBL2 — MYB proto-oncogene like 2
MYBL2 belongs to a gene co-expression module in 4 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
MYBL2's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD19⁺ B cells | Cell Cycle G1/S Cell cycle | CARHSP1, CBX5, CENPM, DNMT1, GMNN, HMGB2, HMGN2, MND1 +8 more | View in SCUBA |
| CD8⁺ T cells | G2/M Checkpoint Cell cycle | CCDC34, CDCA4, CDCA5, MND1, OIP5, RAD54L, RRM2, SAC3D1 +1 more | View in SCUBA |
| Goblet cells | S-phase DNA Replication Cell cycle | ASF1B, BRCA1, CDC6, CENPU, DHFR, FEN1, PCLAF, TK1 +1 more | View in SCUBA |
| Hematopoietic progenitor cells | Late S-phase G2 Entry Cell cycle | ASF1B, CDC45, CDCA5, CENPM, DIAPH3, MND1, PKMYT1, RAD51AP1 +1 more |
About the gene
| Synonyms | B-MYB, BMYB |
|---|---|
| Chromosome | 20: 43667019-43716495 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Cancer-related genes, Predicted intracellular proteins, Transcription factors |
| Molecular function | DNA-binding |
| Biological process | Transcription, Transcription regulation |
Function
Transcription factor involved in the regulation of cell survival, proliferation, and differentiation. Transactivates the expression of the CLU gene
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.