OSCAR — Osteoclast associated Ig-like receptor
OSCAR belongs to a gene co-expression module in 2 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
OSCAR's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Macrophages | Inflammatory Monocyte Activation Inflammatory | ACTN1, ADAM8, AGTRAP, ANXA2, ANXA4, C15orf48, CD44, CD9 +21 more | View in SCUBA |
| Monocytes | FPR1 Innate Sensing Innate immunity | CD300LF, FPR1, FYN, SELPLG, SIRPB1, SLC11A1, SULF2, SYTL1 +1 more | View in SCUBA |
About the gene
| Chromosome | 19: 54094668-54102692 |
|---|---|
| Predicted location | Intracellular, Membrane |
| Essential gene | No |
| Protein class | Predicted intracellular proteins, Predicted membrane proteins |
| Molecular function | Receptor |
Function
Regulator of osteoclastogenesis which plays an important bone-specific function in osteoclast differentiation
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.