PMPCA — Peptidase, mitochondrial processing subunit alpha
PMPCA belongs to a gene co-expression module in 1 of 30 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
PMPCA's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Colonocytes | Mitochondrial Maintenance Mitochondrial & OxPhos | ADGRG1, ATP23, BAD, DNTTIP2, ETFB, FUBP1, ICAM3, LRIG3 +9 more | View in SCUBA |
About the gene
| Synonyms | Alpha-MPP, CLA1, INPP5E, KIAA0123, MAS2, SCAR2 |
|---|---|
| Chromosome | 9: 136410630-136427992 |
| Predicted location | Intracellular |
| Essential gene | Yes |
| Protein class | Disease related genes, Enzymes, Essential proteins, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins |
Function
Substrate recognition and binding subunit of the essential mitochondrial processing protease (MPP), which cleaves the mitochondrial sequence off newly imported precursors proteins
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.