LRIG3 — Leucine rich repeats and immunoglobulin like domains 3
LRIG3 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
LRIG3's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Fibroblasts | Elastin-Fibronectin ECM ECM production | ABI3BP, DDAH2, ELN, FN1, S100A4, SERPINE2, SOD3, SSC5D | View in SCUBA |
About the gene
| Synonyms | FLJ90440, KIAA3016 |
|---|---|
| Chromosome | 12: 58872149-58920504 |
| Predicted location | Intracellular, Membrane |
| Essential gene | No |
| Protein class | Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins |
| Molecular function | Developmental protein |
Function
May play a role in craniofacial and inner ear morphogenesis during embryonic development. May act within the otic vesicle epithelium to control formation of the lateral semicircular canal in the inner ear, possibly by restricting the expression of NTN1 (By similarity)
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.