RBM11 — RNA binding motif protein 11
RBM11 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
RBM11's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD4⁺ T cells | Naive T cell T cell development | AIF1, AK5, APBA2, BEND5, BEX2, C1orf162, CBR3, CYSLTR1 +21 more | View in SCUBA |
About the gene
| Chromosome | 21: 14216130-14228372 |
|---|---|
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Predicted intracellular proteins |
| Molecular function | Developmental protein, RNA-binding |
| Biological process | Differentiation, mRNA processing, mRNA splicing |
Function
Tissue-specific splicing factor with potential implication in the regulation of alternative splicing during neuron and germ cell differentiation. Antagonizes SRSF1-mediated BCL-X splicing. May affect the choice of alternative 5' splice sites by binding to specific sequences in exons and antagonizing the SR protein SRSF1
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.