APBA2 — Amyloid beta precursor protein binding family A member 2
APBA2 belongs to a gene co-expression module in 3 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
APBA2's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD4⁺ T cells | Naive T cell T cell development | AIF1, AK5, BEND5, BEX2, C1orf162, CBR3, CYSLTR1, ENC1 +21 more | View in SCUBA |
| Gamma-delta T cells | Effector Cytokine Secretion Inflammation | ASPH, CCL3, CCL4, CMC1, CYRIA, DTHD1, DTNBP1, FCRL3 +25 more | |
| Natural Killer cells | NK Cell Identity Differentiation | APMAP, COLQ, ETS1, FCMR, FKBP11, GSAP, ICAM2, MRPL10 +2 more | View in SCUBA |
About the gene
| Synonyms | D15S1518E, HsT16821, LIN-10, MGC:14091, MINT2, X11L |
|---|---|
| Chromosome | 15: 28884483-29118315 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Predicted intracellular proteins, Transporters |
| Biological process | Protein transport, Transport |
Function
Putative function in synaptic vesicle exocytosis by binding to STXBP1, an essential component of the synaptic vesicle exocytotic machinery. May modulate processing of the amyloid-beta precursor protein (APP) and hence formation of APP-beta
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.