RGMB — Repulsive guidance molecule BMP co-receptor b
RGMB belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
RGMB's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Goblet cells | Colonocyte Differentiation Program Epithelial development | ASCL2, CAMK1D, CDK6, EDIL3, ENTPD5, FOXN3, HMGCS2, IRF2BP2 +8 more | View in SCUBA |
About the gene
| Synonyms | DRAGON, FLJ90406 |
|---|---|
| Chromosome | 5: 98768650-98798643 |
| Predicted location | Intracellular, Membrane |
| Essential gene | No |
| Protein class | Predicted intracellular proteins, Predicted membrane proteins |
Function
Member of the repulsive guidance molecule (RGM) family that contributes to the patterning of the developing nervous system (By similarity). Acts as a bone morphogenetic protein (BMP) coreceptor that potentiates BMP signaling (By similarity). Promotes neuronal adhesion (By similarity). May inhibit neurite outgrowth
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.