SCUBA

RNF180 — Ring finger protein 180

RNF180 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.

RNF180's module in each cell type

Cell typeModuleShares the module with
Smooth muscle cellsCalcium Handling
Contractility
ASAP2, DDX24, MYCBP2, NBDY, PDE1A, RBM24, RRAS, RYR2 +3 moreView in SCUBA

About the gene

Chromosome5: 64165843-64372869
Predicted locationIntracellular, Membrane
Essential geneNo
Protein classEnzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins
Molecular functionTransferase
Biological processUbl conjugation pathway

Function

E3 ubiquitin-protein ligase which promotes polyubiquitination and degradation by the proteasome pathway of ZIC2

Human Protein Atlas · Open Targets · UniProt

Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.