RSPH3 — Radial spoke head 3
RSPH3 belongs to a gene co-expression module in 1 of 30 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
RSPH3's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Colonocytes | Type I Interferon Inflammation | ACP2, BIRC3, CMPK2, DENND3, EPSTI1, HDAC9, HELZ2, HERC6 +16 more | View in SCUBA |
About the gene
| Synonyms | dJ111C20.1, RSHL2, RSP3 |
|---|---|
| Chromosome | 6: 158972871-159000202 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Human disease related genes, Predicted intracellular proteins |
Function
Functions as part of axonemal radial spoke complexes that play an important part in the motility of sperm and cilia (By similarity). Functions as a protein kinase A-anchoring protein that scaffolds the cAMP-dependent protein kinase holoenzyme. May serve as a point of convergence for MAPK and PKA signaling in cilia.
Human Protein Atlas · Open Targets
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.