SARDH — Sarcosine dehydrogenase
SARDH belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
SARDH's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD8⁺ T cells | Tumor mediated exhaustion Exhaustion | ANXA6, CXCL13, GALM, HNRNPLL, IFNG, ITM2A, PDCD1, PTPN7 +3 more | View in SCUBA |
About the gene
| Synonyms | DMGDHL1, SDH |
|---|---|
| Chromosome | 9: 133663560-133739955 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins |
| Molecular function | Oxidoreductase |
Function
Catalyzes the last step of the oxidative degradation of choline to glycine. Converts sarcosine into glycine
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.