HNRNPLL — Heterogeneous nuclear ribonucleoprotein L like
HNRNPLL belongs to a gene co-expression module in 4 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
HNRNPLL's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD4⁺ T cells | RNA & Chromatin Regulation RNA processing | ATRX, DCP2, DIP2A, KDM5B, NCOR1, OGDH, RIOK3, SAMD9 +7 more | View in SCUBA |
| CD8⁺ T cells | Tumor mediated exhaustion Exhaustion | ANXA6, CXCL13, GALM, IFNG, ITM2A, PDCD1, PTPN7, SARDH +3 more | View in SCUBA |
| Gamma-delta T cells | PLZF Innate-like Effector T cell maturation | DUSP16, GALM, GRAMD1B, MKNK1, NIBAN1, PBX4, PERP, SYNJ2 +1 more | |
| Neutrophils | Myeloid Lipid Remodeling Developmental | ADK, AGPS, ATP8A1, ATP8B4, CLTCL1, DOP1B, ERG, GPD2 +3 more |
About the gene
| Synonyms | HNRPLL |
|---|---|
| Chromosome | 2: 38561969-38603586 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Predicted intracellular proteins |
| Molecular function | Ribonucleoprotein, RNA-binding |
Function
RNA-binding protein that functions as a regulator of alternative splicing for multiple target mRNAs, including PTPRC/CD45 and STAT5A. Required for alternative splicing of PTPRC
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.