SCUBA

ITM2A — Integral membrane protein 2A

ITM2A belongs to a gene co-expression module in 9 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.

ITM2A's module in each cell type

Cell typeModuleShares the module with
CD4⁺ T cellsNFAT activation
TCR/AP1/NFKb pathway
AHI1, ASAP1, BCAT1, BICDL1, CPM, CYP7B1, ETV6, FAM107B +13 moreView in SCUBA
CD8⁺ T cellsTumor mediated exhaustion
Exhaustion
ANXA6, CXCL13, GALM, HNRNPLL, IFNG, PDCD1, PTPN7, SARDH +3 moreView in SCUBA
EndothelialNotch Ligand Signaling
Endothelial cell development
DLL1, KRT222, LTBR, MLKL, SLC2A3, TRA2B, ZC3HAV1, ZNF436View in SCUBA
FibroblastsCD34+ Quiescent Fibroblast
ECM production
ABLIM1, C1QTNF3, CD34, CILP, CLDN11, CPVL, FAIM2, FOLH1 +8 moreView in SCUBA
Gamma-delta T cellsMitochondrial OxPhos
Mitochondrial & OxPhos
ADSL, AP1S1, CD151, COMTD1, COX5A, DDT, DNPH1, DUSP23 +20 more
Innate lymphoid cellsNK/ILC1 Identity
Differentiation
ABCA5, ARHGAP15, CD37, CD96, CD99, CTSD, EPC1, GIMAP2 +17 moreView in SCUBA
Lymphatic endothelialLeukotriene Biosynthesis
Lipid metabolism
ADIRF, AKAP12, APOLD1, EMP1, LTC4S, PLAC9, SNCG, THBDView in SCUBA
Natural Killer cellsNK Cytoskeletal Activation
Cytoskeleton & motility
CAPG, CLNK, COTL1, EVL, GPR82, PEBP1, PGK1, PLEKHO1 +3 moreView in SCUBA
PericytesBMP-SMAD Signaling
Developmental
CTSH, ETS2, EXOC3L2, IL3RA, MCF2L, NDST1, PDE2A, SCARB1 +3 moreView in SCUBA

About the gene

SynonymsBRICD2A, E25A
ChromosomeX: 79360384-79367667
Predicted locationIntracellular, Membrane
Essential geneNo
Protein classPredicted intracellular proteins, Predicted membrane proteins, Transporters

Human Protein Atlas · Open Targets · UniProt

Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.