SDS — Serine dehydratase
SDS belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
SDS's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Monocytes | Tissue-destructive Macrophage Lysosomal & pahgocytosis | ACP5, ANKH, BCAT1, ENG, FABP5, ID3, IL10, KIFC3 +7 more | View in SCUBA |
About the gene
| Synonyms | SDH |
|---|---|
| Chromosome | 12: 113392445-113426301 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins |
| Molecular function | Lyase |
| Biological process | Gluconeogenesis, Lipid metabolism |
Function
Catalyzes the pyridoxal-phosphate-dependent dehydrative deamination of L-threonine and L-serine to ammonia and alpha- ketobutyrate and pyruvate, respectively.
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.