KIFC3 — Kinesin family member C3
KIFC3 belongs to a gene co-expression module in 5 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
KIFC3's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Endothelial | Basement Membrane Assembly ECM remodeling | COL15A1, COL4A1, COL4A2, HSPG2, MGAT4A, NDST1, NOL4L, ORAI2 +4 more | View in SCUBA |
| Gamma-delta T cells | Lysosomal Biogenesis Protein processing & ER | ABI3, APLP2, ATP10A, B3GALT4, BAX, CD63, CTNNA1, DOCK5 +14 more | |
| Macrophages | Inflammatory Monocyte Activation Inflammatory | ANPEP, AQP9, CD300E, CD82, CLEC5A, CXXC5, DDX60L, DHRS9 +25 more | View in SCUBA |
| Monocytes | Tissue-destructive Macrophage Lysosomal & pahgocytosis | ACP5, ANKH, BCAT1, ENG, FABP5, ID3, IL10, LDLRAD4 +7 more | View in SCUBA |
| Neutrophils | NF-κB Signaling Inflammatory | ATP13A3, BMP6, DOCK4, DSE, FLT1, HIVEP2, IRAK2, MAML2 +2 more |
About the gene
| Chromosome | 16: 57758217-57863053 |
|---|---|
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Cancer-related genes, Predicted intracellular proteins |
| Molecular function | Motor protein |
Function
Minus-end microtubule-dependent motor protein. Involved in apically targeted transport (By similarity). Required for zonula adherens maintenance
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.