SDSL — Serine dehydratase like
SDSL belongs to a gene co-expression module in 1 of 30 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
SDSL's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Colonocytes | Mitochondrial Maintenance Mitochondrial & OxPhos | ADGRG1, ATP23, BAD, DNTTIP2, ETFB, FUBP1, ICAM3, LRIG3 +9 more | View in SCUBA |
About the gene
| Synonyms | cSDH, SDS-RS1 |
|---|---|
| Chromosome | 12: 113422380-113438276 |
| Predicted location | Intracellular, Membrane |
| Essential gene | No |
| Protein class | Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins |
| Molecular function | Isomerase, Lyase |
| Biological process | Lipid metabolism |
Function
Catalyzes the pyridoxal-phosphate-dependent dehydrative deamination of L-threonine and L-serine to ammonia and alpha- ketobutyrate and pyruvate, respectively. Also exhibits racemase activity towards L-glutamate and D-glutamate (By similarity).
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.