SGTB — Small glutamine rich tetratricopeptide repeat co-chaperone beta
SGTB belongs to a gene co-expression module in 2 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
SGTB's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD4⁺ T cells | TCR signaling activation TCR/AP1/NFKb pathway | CNST, CORO1B, DAPP1, ECI1, FAAH2, FCMR, GPCPD1, KLHL24 +8 more | View in SCUBA |
| Macrophages | Inflammatory Monocyte Activation Inflammatory | ACTN1, ADAM8, AGTRAP, ANXA2, ANXA4, C15orf48, CD44, CD9 +21 more | View in SCUBA |
About the gene
| Synonyms | FLJ39002, Sgt2 |
|---|---|
| Chromosome | 5: 65665928-65723035 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Predicted intracellular proteins |
| Molecular function | Chaperone |
Function
Co-chaperone that binds directly to HSC70 and HSP70 and regulates their ATPase activity
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.