SLC52A1 — Solute carrier family 52 member 1
SLC52A1 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
SLC52A1's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Enterocytes | Epithelial junction polarity Migration & adhesion | CXADR, FRMD3, IL13RA1, KIF3B, MARVELD3, NEDD9, PTPRD, RAB6A +5 more | View in SCUBA |
About the gene
| Synonyms | FLJ10060, GPCR42, GPR172B, hRFT1, PAR2, RFVT1 |
|---|---|
| Chromosome | 17: 5032600-5052009 |
| Predicted location | Membrane |
| Essential gene | No |
| Protein class | Disease related genes, Human disease related genes, Metabolic proteins, Predicted membrane proteins |
| Molecular function | Host cell receptor for virus entry, Receptor |
| Biological process | Transport |
Function
Plasma membrane transporter mediating the uptake by cells of the water soluble vitamin B2/riboflavin that plays a key role in biochemical oxidation-reduction reactions of the carbohydrate, lipid, and amino acid metabolism. Humans are unable to synthesize vitamin B2/riboflavin and must obtain it via intestinal absorption. (Microbial infection) May function as a cell receptor to retroviral envelopes similar to the porcine endogenous retrovirus (PERV-A)
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.