SCUBA

FRMD3 — FERM domain containing 3

FRMD3 belongs to a gene co-expression module in 4 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.

FRMD3's module in each cell type

Cell typeModuleShares the module with
EnterocytesEpithelial junction polarity
Migration & adhesion
CXADR, IL13RA1, KIF3B, MARVELD3, NEDD9, PTPRD, RAB6A, SLC41A2 +5 moreView in SCUBA
FibroblastsElastic Fiber ECM
ECM production
ADD3, ASPA, FBLN5, PLTP, SLC29A1, SLIT2, SVEP1, TNXBView in SCUBA
Glial cellsENS Developmental TFs
Development
ERBIN, HAND2, LRRC4C, MAP4K4, PYGL, SEC11C, SLC25A36, TBX3 +2 moreView in SCUBA
PericytesPericyte Identity
Developmental
ADIRF, CLMN, GPX3, HIGD1B, KLHL23, MAP3K20, PLCE1, TINAGL1View in SCUBA

About the gene

SynonymsEPB41L4O, MGC20553
Chromosome9: 83242990-83538546
Predicted locationIntracellular, Membrane
Essential geneNo
Protein classPredicted intracellular proteins, Predicted membrane proteins

Function

Putative tumor suppressor gene that may be implicated in the origin and progression of lung cancer

Human Protein Atlas · Open Targets · UniProt

Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.