SRPK3 — SRSF protein kinase 3
SRPK3 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
SRPK3's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Hematopoietic progenitor cells | ILC3/γδT Priming Lymphcyte development | C2CD4D, CCL1, CCR1, CD2, CD7, CHI3L2, FGR, GPR18 +8 more |
About the gene
| Synonyms | MSSK1, STK23 |
|---|---|
| Chromosome | X: 153776412-153785732 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Enzymes, Metabolic proteins, Predicted intracellular proteins |
| Molecular function | Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase |
| Biological process | Differentiation, Myogenesis |
Function
Serine/arginine-rich protein-specific kinase which specifically phosphorylates its substrates at serine residues located in regions rich in arginine/serine dipeptides, known as RS domains. Phosphorylates the SR splicing factor SRSF1 and the lamin-B receptor (LBR) in vitro. Required for normal muscle development (By similarity)
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.